The CPLG Guidance Committee monitors current and emerging global regulatory guidance and guidelines related to Clinical Pharmacology issues.  The Committee identifies relevant guidelines on which to provide joint IQ comments, creates ad hoc teams of experts to develop, compile, and build consensus on comments, and creates final compiled comments for submission to regulatory agencies, based on IQ member feedback.  The Committee also collaborates with other IQ Leadership Groups and Working Groups to coordinate and provide CPLG input to joint comments being collected across IQ groups and disciplines, to respond to broad, cross-cutting regulatory guidelines.